Publications

Here you will find the most relevant publications about APO010 and the science behind.

More news releases from Oncology Venture.

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2017 – Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis

Mou, H. (2017). Proceedings of the National Academy of Sciences, 114(14), 3648–3653. Read full publication

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2017 – Prospects for combining targeted and conventional cancer therapy with immunotherapy

Gotwals, P. (2017). Nature Reviews Cancer. Read full publication

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2016 – Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation

Arce-Sillas, A. (2016). Journal of Immunology Research. Read full publication

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2015 – Bortezomib improves adoptive T-Cell therapy by sensitizing cancer cells to FasL cytotoxicity

Shanker, A. (2015). Cancer Research, 75(24), 5260–5272. Read full publication

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2015 – Galectin-3 Shapes Antitumor Immune Responses by Suppressing CD8+ T Cells via LAG-3 and Inhibiting Expansion of Plasmacytoid Dendritic Cells

Kouo, T. (2015). Cancer Immunology Research, 3(4), 412–423. Read full publication

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2015 – The role of CD95 and CD95 ligand in cancer

Peter, M. E. (2015). Cell Death and Differentiation, 22(4), 549–559. Read full publication

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2015 – A time to kill: Targeting apoptosis in cancer

Koff, J. L. (2015). International Journal of Molecular Sciences. Read full publication

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2014 – Gemcitabine sensitizes lung cancer cells to Fas/FasL system-mediated killing

Siena, L. (2014). Immunology, 141(2), 242–255. Read full publication

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2013 – Fas/CD95-Induced Chemokines Can Serve as “ Find-Me” Signals for Apoptotic Cells

Cullen, S. (2013). Molecular Cell, 49(6), 1034–1048. Read full publication

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